Hopkins researchers recommend reclassifying psilocybin from schedule I to schedule IV

#1
https://hub.jhu.edu/2018/09/26/psilocybin-scheduling-magic-mushrooms/
In an evaluation of the safety and abuse research on the drug in hallucinogenic mushrooms, Johns Hopkins researchers suggest that if it clears phase III clinical trials, psilocybin should be re-categorized from a schedule I drug—one with no known medical potential—to a schedule IV drug such as prescription sleep aids, but with tighter control. Their analysis is summarized in the October print issue of Neuropharmacology.
Following the Controlled Substances Act of 1970, any drug with the potential for abuse is categorized based on criteria that take into account whether the drug has accepted medical use, and its safety and the potential for abuse. Schedule IV drugs are those that have a low potential for abuse or dependence.

Although preliminary research studies suggest that psilocybin may be effective for smoking cessation and for disorders such as cancer-specific depression and anxiety, it must clear phase III clinical trials before the Food and Drug Administration can be petitioned to reclassify it.
Studies in animals and humans both show low potential for abuse, the researchers say. When rats push a lever to receive psilocybin, they don't keep pushing the lever like they do for drugs such as cocaine, alcohol, or heroin. When it comes to human studies, people who have used psilocybin typically report using it a few times across their lifetime.

As for safety, studies show it frequently falls at the end of the scales with the least harm to users and society, say the researchers. Psilocybin also is lowest in the potential for lethal overdose as there is no known overdose level. "We should be clear that psilocybin is not without risks of harm, which are greater in recreational than medical settings, but relatively speaking, looking at other drugs both legal and illegal, it comes off as being the least harmful in different surveys and across different countries," says Johnson.vi
https://motherboard.vice.com/en_us/article/3keppn/prescribe-magic-mushrooms-depression-johns-hopkins
Researchers have been using psilocybin to successfully treat both depression and addiction in clinical trials over the past few years. In a 2016 study, the same team of Johns Hopkins University researchers administered magic mushrooms to terminal cancer patients with the goal of alleviating their end-of-life anxiety and depression.

“Studies showed that psilocybin caused significantly and clinically significant reductions in symptoms of depression and anxiety lasting at least six months after psilocybin administration,” the newly published study explained.
Researchers have had success using medicinal magic mushrooms in controlled settings, where the dose is regulated and administered by a trained clinician, a psychologist or trained therapist guides the recipient through the experience, and there’s very specific goals for the therapy. In the case of the cancer patients, terminal patients experienced guided trips with the goal of helping them confront and overcome their fear of death. A weekend trip while camping in the woods this is not.

The study is also one step in a long process. Depressed and anxious people won’t be able to walk into a clinic and experience a healing drug trip for years, or possibly decades, if at all. Johnson said reclassification could take “three to 10 years." Studies, which haven't been done yet or that are just beginning, would need to be completed and the results would need to look favorable and consistent.
 
#2
Really hope this can have a use for OCD with it's affects on anxiety. Would be much safer then the meds they use now.

Hopefully the general public can get access to it sooner rather then later.
 
#4
My concern is that the drug friggin strong.

It has a very potent effect and lasts freaking forever.

But it's interesting that it doesn't have many downsides aside from that.

I don't know about sleep aids... The hallucinating is real and your mind works extra active.

Here's how I can describe it when i took it.

It felt like I was super happy to be alive and part of the world, like it made me giddy. Me and my boy laughed at everything, geeked out...

However, this isn't the drug you wanna be on if somebody told you some life changing bad news, shit would break you
 
#8
My concern is that the drug friggin strong.

It has a very potent effect and lasts freaking forever.

But it's interesting that it doesn't have many downsides aside from that.

I don't know about sleep aids... The hallucinating is real and your mind works extra active.

Here's how I can describe it when i took it.

It felt like I was super happy to be alive and part of the world, like it made me giddy. Me and my boy laughed at everything, geeked out...

However, this isn't the drug you wanna be on if somebody told you some life changing bad news, shit would break you
Yeah I think even people hardcore into wanting psychadelics legalized acknowledge how powerful they are and that recreational use is far less advised or even dangerous vs. supervised use.
 
#9
I've heard this and LSD have shown promising results treating depression (both with full and microdoses).

Now if only our politicians actually based drug policy on scientific consensus rather than that Reefer Madness ad. But alas, even though states have been making progress, at the federal level marijuana is still considered Schedule I. Pure nonsense.
 

Krejlooc

Dreamcast Porno Party
Member
#11
Like i said in that other topics, mushrooms were like a religious experience for me. Changed my mindset forever. I dont regret trying them at all.

Would never recommend for casual consumption tho.
 
#12
Had a great time with mushrooms. It really clears up my mindset for about a month before I get back to normal. Would love for it to be legal.
 
#13
Like i said in that other topics, mushrooms were like a religious experience for me. Changed my mindset forever. I dont regret trying them at all.

Would never recommend for casual consumption tho.
Their definitely a "once in a blue moon" sort of thing.

Never ever had a bad trip though, acid and shrooms were always great mind opening experiences. Always good to change your perspective even if just for a little while.
 
#14
My concern is that the drug friggin strong.

It has a very potent effect and lasts freaking forever.

But it's interesting that it doesn't have many downsides aside from that.

I don't know about sleep aids... The hallucinating is real and your mind works extra active.

Here's how I can describe it when i took it.

It felt like I was super happy to be alive and part of the world, like it made me giddy. Me and my boy laughed at everything, geeked out...

However, this isn't the drug you wanna be on if somebody told you some life changing bad news, shit would break you
It can be administered in micro doses where you don't feel fucked up but it still has a therapeutic effect.
 
#15
Like i said in that other topics, mushrooms were like a religious experience for me. Changed my mindset forever. I dont regret trying them at all.

Would never recommend for casual consumption tho.
Same for me and I agree, you have to respect it because it's very powerful and will make you its bitch if you are not responsible and careful. Bad trips are not fun...
 

Krejlooc

Dreamcast Porno Party
Member
#16
Same for me and I agree, you have to respect it because it's very powerful and will make you its bitch if you are not responsible and careful. Bad trips are not fun...
I had a bad LSD trip once. It was absolutely miserable. I just wanted it to end, and it kept going for like 8 hours. Describe it was a relentless trip.

When I did mushrooms, me and my best friends had planned out the entire night and did it in a quiet, private setting with a baby sitter to make sure we didn't hurt ourselves or anything. It was honestly one of the most insanely fun and liberating nights of my life. Like I said, it really did change my mindset forever, I feel like I'm a much more open person.

Same time, I think there are people who would honestly never be mentally prepared for something like that.

I see your avatar. DMT is the last "major" drug I ever did way back in college about 10 years ago. THAT is an insane trip. Freaky insane.
 
#17
I had a bad LSD trip once. It was absolutely miserable. I just wanted it to end, and it kept going for like 8 hours. Describe it was a relentless trip.

When I did mushrooms, me and my best friends had planned out the entire night and did it in a quiet, private setting with a baby sitter to make sure we didn't hurt ourselves or anything. It was honestly one of the most insanely fun and liberating nights of my life. Like I said, it really did change my mindset forever, I feel like I'm a much more open person.

Same time, I think there are people who would honestly never be mentally prepared for something like that.

I see your avatar. DMT is the last "major" drug I ever did way back in college about 10 years ago. THAT is an insane trip. Freaky insane.
We had similar experiences then, I took 4 tabs when I was 18 and experienced ego death, not fun when you're not educated on the subject! And yes it just went on and on..Very dumb of me.

I have only snorted smaller amounts of DMT a couple of times but yeah even that small amount, nothing compares to that power...

And yup, hallucinogens could just break some people, it's not for everyone, especially those that don't like giving up control.
 
#18
I've heard this and LSD have shown promising results treating depression (both with full and microdoses).

Now if only our politicians actually based drug policy on scientific consensus rather than that Reefer Madness ad. But alas, even though states have been making progress, at the federal level marijuana is still considered Schedule I. Pure nonsense.
I used lsd a few times, I know it’s dangerous if abused so I’ll take a tab or two for 2 weeks then go cold turkey for like 8 months to a year. When my mom passed 2 years ago I was so depressed I would cry every day. I took some and felt better the next day. After a few weeks I realized I that although I was still sad I wasn’t depressed like before. I didn’t know about the antidepressant part before taking it. But yeah the effects lasted a few months.
 
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